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The $45 Billion Industry Everyone's Ignoring
By Rob Fannon, editor, Phase 1 Investor

March 07 , 2008

More than two-thirds of all medical decisions are based on a lab test.

That may sound like a big number. But I expect this figure to explode in the next decade, perhaps to even 100%. The diagnostics industry is the most rapidly changing sector in modern medicine...

Health care investors used to regard diagnostics as the redheaded stepchild of medicine. The margins and overall economics of routine testing products – tests that cost a few bucks and measure cholesterol or blood-sugar levels – just aren't all that attractive.

But these "one size fits all" tests are rapidly giving way to more accurate, sophisticated, and individualized genetic tests. With such improvements, the price tags on these services are skyrocketing.

For example, take the latest diagnostic product used to determine treatment regimens for breast cancer...

Chemotherapy is one of the most grueling treatments in modern medicine, one that causes nausea, hair loss, infertility, and more. Even so, most cancer patients willingly face such harsh side effects in hopes of getting better.

But what if your doctor told you the chances of you getting any benefit from subjecting your body to such chemical warfare was only 4%? I'd pass on the chemo and advise my family members to do the same...

Yet doctors have had no way to determine who would and would not respond to chemotherapy. So the thinking has been treat first, ask questions later. But now, for the first time, doctors can prescreen patients that will respond to chemo based on the results of a new test that probes their cancer's molecular "fingerprint."

Tissue samples are run through a 16-gene test panel to identify the small percentage of patients that will actually derive a clinical benefit from the physically and mentally taxing chemotherapy regimen.

How much does a test like this cost? About $3,650 a pop.

That's worlds away from your standard $10 cholesterol test. But the information provided in the test is much more valuable, too. The doctor doesn't have to guess whether the patient will benefit. The patient understands the risks and payoffs of such a nasty treatment beforehand. And the insurance company would much rather cough up a few thousand bucks up-front for the test in order to skip out on a $20,000–$50,000 course of chemo.

Why You May Never Take a Regular Drug Again

Tracking Down the Superbug

I recommended the maker of this test to my Phase 1 readers several months ago. We're up about 10% on the position. Of course, this company is just one of many players in the fast-growing diagnostics industry, which rakes in about $45 billion a year.

Here are a few of the biggest players:

Company

Ticker
Market Cap
Price/
Earnings
Profit Margin

Quest

DGX

$9 billion
26
5%

LabCorp

LH

$9 billion
20
11%

Bio-Rad

BIO

$2.5 billion
26
6%

The diagnostics industry now offers faster, cheaper, and more accurate genetic technologies... with much more attractive market economics. It's the perfect place for health care investors in the next decade and beyond.

Good investing,

Rob Fannon

Wal-Mart Defies Wall Street
Wal-Mart Stores Inc. is reaping a bonanza from a U.S. economy teetering on the brink of recession.

Wal-Mart, the world's largest retailer, said today that sales at stores open at least a year rose 2.6 percent in February, topping its estimate of as much as 2 percent. Sales at Gap Inc., J.C. Penney Co. and Nordstrom Inc. fell. Read on...

Billionaire Buys Municipals
Investor Wilbur Ross has purchased $1bn of US municipal bonds, a sign that some large investors are snapping up these investments after a recent selloff, reports the Wall Street Journal.

Ross wouldn't comment on who sold the bonds to him but people familiar with the matter said he purchased the portfolio of bonds from hedge fund Duration Capital Management, which operates two hedge funds and has been selling bonds to try to stay afloat, according to the Journal. A Duration representative wouldn't comment other than to say that the hedge funds are still in business. FT ($) Read on...


Mining equipment giants Joy Global and Bucyrus at 52-week highs.

Credit Crunch Part II... Merrill Lynch, Morgan Stanley, Lehman Brothers, UBS, Wachovia Bank, Legg Mason, and Blackstone at new lows.
Freddie Mac and Fannie Mae at 13-year lows.
Last Change 52-Wk
S&P 500 1313.16 -1.54% -5.66%
Oil (USO) 83.73 0.52% 63.25%
Gold (GLD) 93.71 -4.10% 45.74%
Silver (SLV) 96.57 -1.18% 50.19%
US Dollar 74.80 -1.06% 10.86%
Euro 1.497 0.98% 13.61%
VIX 21.88 -4.99% 96.23%
HUI 477.79 2.45% 32.05%
10-year yield 3.86% -0.04 -0.77
Company Sym Industry

CS Swiss Franc

FXF

ETF

ABN AMRO

ABN

bank

Permian Basin

PBT

oil & gas

Converted Organics

COIN

agriculture

Konami

KNM

video games

Randgold

GOLD

gold

Kinder Morgan

KMR

oil & gas

Bucyrus

BUCY

heavy equipment

James River

JRCC

coal

Syngenta

SYT

agriculture

Eldorado Gold

EGO

gold

GeoResources

GEOI

oil & gas

HQ Sustainable

HQS

fish products

American Realty

ARL

REIT

BP Prudhoe Bay

BPT

oil & gas

Solitario Resources

XPL

gold & silver

CS Euro

FXE

ETF

Capstone Turbine

CPST

industrial equip

First Trust Materials

FXZ

ETF

Joy Global

JOYG

mining equip

Agnico-Eagle

AEM

gold

Highveld Steel

HSVLY

steel

Advertisement

Company Sym Industry

AmerisourceBergen

ABC

pharma

Legg Mason

LM

asset mgmt

Electronic Data

EDS

IT

Apex Silver

SIL

silver

UBS

UBS

bank

Wachovia

WB

bank

DaVita

DVA

health care

Radian

RDN

insurance

Merrill Lynch

MER

investment bank

Morgan Stanley

MS

investment bank

Bristol-Myers

BMY

Big Pharma

R.H. Donnelley

RHD

publishing

Cintas

CTAS

uniforms

National Semi

NSM

semiconductors

Jackson Hewitt

JTX

taxes

Safeco

SAF

insurance

Blackstone

BX

private equity

Lamar Advertising

LAMR

billboards

Nortel Networks

NT

networks

First Mercury

FMR

insurance

Lehman Brothers

LEH

investment bank

Bank of Montreal

BMO

bank

Fannie Mae

FNM

mortgages

China Eastern

CEA

airline

Raymond James

RJF

asset mgmt

Brown & Brown

BRO

insurance

King Pharma

KG

pharma

JPMorgan

JPM

bank

Freddie Mac

FRE

mortgages

Alcatel-Lucent

ALU

technology

Saks

SKS

luxury retail

iStar Financial

SFI

REIT

Boyd Gaming

BYD

casinos

Crocs

CROX

rubber shoes

Vail Resorts

MTN

snow skiing

Belo

BLC

newspapers

Euronet

EEFT

ATMs

Unitrin

UTR

car insurance

Anthracite

AHR

REIT

Huaneng Power

HNP

utilities

AIG

AIG

insurance

Meredith

MDP

media

Calamos

CLMS

asset mgmt

Novartis

NVS

Big Pharma

Friedman Billings

FBR

REIT

Sepracor

SEPR

pharma

Borders Group

BGP

bookstore

Tootsie Roll

TR

candy

Best Buy

BBY

retail

Triarc

TRY

restaurants

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