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The Buy Signal You've
Waited For

By Rob Fannon, editor, Phase 1 Investor
July 25, 2008

Genentech has reigned as king of the biotech industry for more than three decades.

A three-hour chat in a San Francisco pub launched the company in 1976. On its first day of trading in 1980, the stock tripled – and has risen 20-fold since. Today, Genentech's portfolio includes three of the world's top-selling biotech drugs – Avastin ($2.5 billion per year), Herceptin ($1.7 billion), and Rituxan ($2.5 billion).

But the king of biotech is now a buyout target. While I don't believe the takeout bodes well for buyer or seller, the deal should mean big profits for biotech investors. Let me explain...

In 1990, Swiss drug company Roche acquired a majority stake in Genentech. Roche became Genentech's exclusive European distributor. Today, Genentech's drugs represent 30% of Roche's pharmaceutical sales. And as Genentech's largest shareholder, Roche has multiplied its money about 40 times in two decades.

As part of the deal, Roche allowed Genentech to maintain the entrepreneurial spirit so critical to its early success. In return, the Big Pharma's financial backing allowed Genentech to focus on making drugs, not meeting Wall Street's quarterly numbers.

The win-win relationship thrived for nearly two decades. But this past Monday, Roche launched a bid to acquire the 44% of Genentech shares it didn't already own.

Apparently, the takeout move caught Genentech executives off-guard. Roche insists it's interested in boosting its research engine... not downsizing. But our inside sources tell us many employees are dusting off their resumes in preparation for a post-merger shakeout. Whether it's voluntary or not, a mass exodus of the Genentech talent pool won't help Roche.   

And I think the minimum $40 billion outlay is a mistake. Roche's new trigger-happy CEO, Severin Schwan, led the diagnostics division on several hundred-million-dollar buyouts. Now he's courting another acquisition when the money could be better spent on research.

As I wrote earlier, Genentech is more like a Big Pharma player than the tiny biotech it once was. It focuses on expanding its existing drugs in new indications, rather than discovering new drugs. Since Roche already reaps the benefits of Genentech's portfolio, gobbling up the rest of the shares adds little value.

And Roche is going to have to pay up. The company's initial $89-per-share offer gave a measly 9% premium to Genentech's shareholders. The market thought it was a low-ball bid and pushed shares as high as $94.50. My guess is the bidding will stop around $100 per share, valuing Genentech at $100 billion.

While I believe the bid is a bad move for Roche – and not a great proposal for Genentech shareholders – this mega-deal is actually good for the entire biotech industry... and its investors.

With Genentech gone, the top of the biotech food chain is empty. Many investors will be searching for new spots to park their biotech cash. And sector valuations are on the rise. Both major biotech indexes – the Nasdaq Biotech Index and AMEX Biotech Index – are up more than 7% in just a few weeks.

And as my colleague Steve Sjuggerud recently noted, the proposed acquisition has propelled the biotech sector from the back pages to the front pages of every major newspaper.

Biotech's Next Big Bull Market Starts Now

Biotech Is Setting Up for Another 1,347% Rally

Small-cap biotechs are cheap right now. So I'd be willing to bet the sector could jump 25% or more in the coming months. And big-cap names like Biogen (BIIB), Genzyme (GENZ), and Elan (ELAN) have jumped to the top of Big Pharma's short list of buyout candidates.

If you're thinking of dabbling in the biotech sector, Roche's bid for Genentech just may be the buy signal you're waiting for.

Good investing,

Rob Fannon

Bull Market in Chinese Teachers
When the Yonkers, New York, public schools sought to hire a Chinese-language teacher, Superintendent Bernard Pierorazio expected to fill the job within weeks. He was off by two years.

Schools in the U.S. face a shortage of instructors in Chinese, stymieing efforts to prepare pupils for careers tied to China, the world's fastest-growing economy. The Schenectady, New York, schools will require only a third of pupils in grades 5 and 6 to take Chinese because the district couldn't find instructors for all the students, Ron Hamelin, world-languages coordinator, said in an interview on July 18. Read on...

Chinese Tighten Mortgage Lending Standards
Chinese officials and government economists have warned domestic banks to tighten their mortgage lending criteria after the US government's action to prop up Fannie Mae and Freddie Mac, the giant mortgage agencies.

Liu Mingkang, China's top banking regulator, has in recent days urged the country's state-owned commercial banks to beware of risks in the real estate sector and ordered them to tighten loan approval processes. FT ($) Read on...


Novartis leads medical stocks higher... Vital Signs, Owens & Minor, Alcon, Varian Medical, and ConMed hit new highs.
Stretched consumers rent-to-own... Rent-A-Center hits a 52-week high.

Mexican fast-food restaurant Chipotle misses numbers, hits all-time low.

Earnings today... Legg Mason, Alexander & Baldwin, Honda, T. Rowe Price.
Last Change 52-Wk
S&P 500

1282.18

+0.41%

-15.15%

Oil (USO)

100.02

-3.19%

+81.33%

Gold (GLD)

90.57

-2.68%

+34.24%

Silver (SLV)

171.90

-3.20%

+30.18%

U.S. Dollar

72.78

+0.42%

-9.13%

Euro
1.57
-0.54%
+13.52%
VIX

21.31

+0.61%

+14.88%

HUI

408.98

-5.44%

+12.14%

10-Year Yield

4.15%

0.05

-0.67

Company Sym Industry

Vital Signs

VITL

medical equip

Teledyne

TDY

aerospace

Omega Protein

OME

supplements

Novartis

NVS

Big Pharma

Owens & Minor

OMI

medical equip

IBM

IBM

computers

Qualcomm

QCOM

telecom

Alcon

ACL

medical equip

Natl Presto

NPK

appliances

HireRight

HIRE

staffing

Norfolk Southern

NSC

railroad

ConMed

CNMD

medical equip

Varian Medical

VAR

medical equip

Rent-A-Center

RCII

rent-to-own

Advertisement

Company Sym Industry

Chipotle

CMG

burritos

Lundin Mining

LMC

mining

Banro

BAA

gold

FortuNet

FNET

gaming machines

Sturm, Ruger

RGR

guns

Convergys

CVG

consulting

Gramercy Capital

GKK

REIT

Taser

TASR

stun guns

Expeditors Intl

EXPD

air freight

Templeton Russia

TRF

ETF

Scholastic

SCHL

publishing

A New Bull Market Begins in Four Months
July 24, 2008

Commodity Q&A: Big Oil's Top Five Companies
July 23, 2008

The Best Indicator for Trading Oil Stocks
July 22, 2008

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