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Three Ways to Use Biotech to Get Your Portfolio Back on Track
By Rob Fannon, editor, Phase 1 Investor
December 19, 2008

I looked out at a sea of shell-shocked faces... no emotion, no interest, no curiosity... just blank stares.

Earlier this month, my publisher hosted its annual conference in Hong Kong. The meeting at the Four Seasons was the most somber I've ever attended. The audience and most of my colleagues were bearish to the point of paralysis.

But even as I reeled with jet lag, I was impatient to get to get to the podium. I have three huge ideas to get your portfolio back on track in 2009, and I couldn't wait to share them...

1. It's a great time to buy biotech's biggest names.

As my colleague Dr. George Huang explained last month, the iShares Nasdaq Biotechnology Fund (IBB) has outperformed 99% of ETFs this year. It's down about 15%, compared with a 40% drop on the S&P 500. Biotech drugs are immune to hard economic times. Patients need drugs from these companies or they will die. So biotech will continue to outperform more vulnerable industries.

IBB holds a chunk of Big Biotech – profitable companies that are growing sales and generating tons of cash. Top companies like Novo Nordisk (NVO), Biogen (BIIB), and Genzyme (GENZ) are trading for less than five times sales (about 40%-50% less than they traded for one year ago). IBB is the easiest way to play the sector that will lead the market recovery in 2009.

2. It's an even better time to bet against the market's worst.

As I wrote last week, the credit crunch is finally weeding out biotech's weakest players.

These days, sketchy management teams with crappy drugs won't be able to woo naïve investors into spending big bucks on medical pipedreams. Once these worthless biotechs get the boot, the market will allocate funds to well-run outfits with worthy products. This will push up stock prices sector-wide (see No.1). It'll also give us a rich opportunity to short undeserving biotech outfits.

3. We can make easy money following Big Pharma's cash.

With capital tight, the drug industry is trying to stretch research dollars as far as possible. So drugmakers are turning to contract research organizations – or CROs – in droves. CROs handle everything from early lab and animal tests to new drug applications at the FDA. CROs are 30% more efficient than in-house research.

The top players in the CRO business have more work than they can keep up with – including a $9 billion backlog for the top three players. The CRO industry is growing 12%–15% per year. But shares are priced for death...

In the past six weeks, publicly traded CROs are down an average 35%. As I told the audience in Hong Kong, such carnage is our opportunity. I believe 30%-50% gains are possible in 2009 by holding a basket of top CRO players in the industry. Start with the industry leader in early-stage drug development – Covance (CVD).

Why CROs Are the Safest Way to Profit from Drug Discovery

You'll Never Guess the Top- Performing Sector of 2008

After ticking off my best money-making ideas, I figured I'd be mobbed with questions. Nope. Nobody took notes during my presentation, let alone asked for more details.

But I wasn't fazed. To me, that's the most bullish endorsement I could've hoped for.

Good investing,

Rob Fannon

Residents Flee California
For the fourth year in a row, more residents left the Golden State than moved here from other states, according to a report released Wednesday by the California Department of Finance.

The outflow – last seen during the economic and social struggles of the 1990s – started when it became too expensive for most people to buy homes in the state, and has kept going throughout the bust with the loss of so many jobs. Read on...

Japan Car Sales Faceplant
Japan's vehicle sales next year may fall to the lowest in 31 years as unemployment and the economic slowdown keep drivers out of showrooms.

Sales of trucks, buses, cars and minicars, may fall 4.9 percent to 4.86 million vehicles in 2009 from an estimated 5.11 million this year, the Japan Automobile Manufacturers Association said in a statement today. The tally would be the lowest since 1978, when automakers sold 4.68 million units. Read on...


Copper falls 5% to reach new 2008 low.
Oil falls below $36 for the first time since 2004... U.S. Oil Fund hits all-time low.
Volatility continues to recede... VIX closes below 50, at lowest point in two months.

Holiday shoppers go thrifty... Dollar Tree hits 52-week high.

Earnings today... CarMax, Darden Restaurants.

Last Change 52-Wk
S&P 500

904.42

-0.96%

-37.84%

Oil (USO)

34.81

-4.47%

-51.05%

Gold (GLD)

85.43

+1.15%

+7.80%

Silver (SLV)

11.29

+2.36%

-18.78%

U.S. Dollar

77.83

-0.97%

+0.33%

Euro
1.47
+1.97%
+2.04%
VIX

49.84

-4.83%

+120.14%

HUI

291.95

-1.49%

-23.60%

10-Year Yield

2.19%

-0.16

-1.03

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Cali Water Service

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Repros Thera

RPRX

biotech

Long Term Treasury

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Thoratec

THOR

medical equip

Shenandoah Tele

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telecom

Dollar Tree

DLTR

dollar store

Company Sym Industry

First Community

FCCO

bank

Berkshire Bancorp

BERK

bank

Fidelity Bancorp

FSBI

bank

Take-Two Interactive

TTWO

video games

Community Valley

CVLL

bank

U.S. Oil

USO

oil

North Central Banc

FFFD

bank

Beverly Natl

BNV

bank

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Your Second Chance to Buy the Best Yield in the Market
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Weekend Edition: The Ultimate Investment Fantasy
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