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For the Best Bargains, Look Abroad

By Rob Fannon, editor Phase 1 Investor
Friday, October 10, 2008

Last week, I bounced through Europe by air, rail, and taxi with fellow biotech analyst George Huang. We hit five companies... in five countries... in seven days.
 
You might think we're crazy to leave home amid the financial crisis. But we've been sizing up European biotech opportunities for about a year now. The risk-aversion bug sucked the European markets' appetite for biotech completely dry in the last 12 months. So European biotech stocks are way cheaper than their U.S. counterparts. They have much richer pipelines. And a few recent events have confirmed our hunch that Europe is biotech's latest hotspot...
 
Investor interest in European biotech might be about as low as it gets right now. But the acquisitions market is heating up. Cash-rich European drugmakers are drooling over the dwindling valuations in the biotech sector.
 
Of course, the biggest pending acquisition by a European drugmaker is Switzerland-based Roche's $43.7 billion takeover of U.S. biotech Genentech, the first and most prominent company in the industry. This summer, a few smaller deals continued the trend...
 
Ireland-based Shire Pharmaceuticals scooped up Berlin-based biotech Jerini for a whopping 74% premium. The stock had wallowed at depressed levels for nearly two years, and Shire was interested in getting access to a few of Jerini's protein-based drugs. But why deal with complex partnership or licensing terms when it's easier and cheaper to simply to buy the company outright?
 
The same line of thinking applied to two additional European takeouts: France-based Sanofi-Aventis paid a 65% premium to buy British vaccine company Acambis in late July. Earlier in the month, Swiss drugmaker Novartis bought out Swiss biotech Speedel for a 94% premium.
 
Jerini and Speedel – two of the summer takeouts – had been on our short list. So you can see our hurry to hop on a transatlantic flight. Here's what we found...
 
Public financing and other types of biotech funding are down 70% from this time last year in Europe. So the best companies have to hold plenty of cash. Most of the biotechs we visited had about half their market cap in cash... enough money to keep the lights on for roughly two years.
 
Also, all the companies we visited offered a product near market launch along with multiple projects behind the most advanced drug in development. In other words, all the companies had "multiple shots on goal."
 
While they may have cash and plenty of promising projects, none of the companies we visited can catch a break in the public markets. Their stocks are down an average of 49% over the last year... One is 78% below its year-ago level.
 
Biotechs with cash – and deep clinical pipelines – are the stocks to own right now. The fact that they're cheap makes our timing that much more perfect. It's a win-win scenario: If markets improve, these stocks will explode as independent entities. And if valuations stay cheap, these names will remain at the top of the takeout list for Big Pharma – particularly European drugmakers.
 
Investors who buy in at today's levels will likely collect a few double-digit premiums before the year is out. If not, they'll be rewarded when positive sentiment returns to the sector.
 
Most American investors don't know or care about the European biotech sector right now. Conference halls are empty when European CEOs appear on the U.S. biotech presentation circuit.
 
So if you're interested in beating the crowd to this story, make sure you have a brokerage account that can trade stocks on the London, Swiss, and Brussels stock exchanges. As Big Pharma picks off more of these top-quality biotechs at double- and triple-digit buyout premiums, American investors will start digging abroad, and prices will soar.
 
Good investing,
 
Rob Fannon




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Market Notes
The General breaks down... General Motors drops below $6 to a 58-year low.
 
Investors want their money back... Asset managers Oppenheimer, T. Rowe Price, TD Ameritrade, and Legg Mason hit 52-week lows.
 
Big Pharma drops... Pfizer, Merck, Eli Lilly, Sanofi-Aventis, and GlaxoSmithKline at new lows.
 
Earnings today... General Electric.
Market Watch
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52-Wk
S&P 500 1221.53 +1.28% +10.12%
Oil 37.77 +1.53% -2.75%
Gold 135.20 -0.13% +13.44%
Silver 27.93 +0.43% +47.86%
US-Dollar 80.67 -0.81% +8.09%
Euro 1.32 +0.64% -12.10%
Volatility 19.39 -9.22% -8.19%
Gold Stocks 564.53 +1.34% +10.57%
10-Year Yield 3.00 +1.35% -9.64%

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52-Wk
USA 122.56 +1.28% +10.17%
Canada 30.44 +1.33% +13.84%
Russia 21.63 +2.27% +16.67%
India 37.73 +1.92% +19.97%
Israel 16.47 +0.86% +9.65%
Japan 10.58 +0.95% +7.41%
Singapore 13.88 +1.02% +19.24%
Taiwan 14.72 +1.59% +17.76%
S. Korea 56.56 +1.67% +22.80%
S. Africa 70.85 +3.89% +22.94%
China 45.06 +1.37% +0.13%
Lat.America 52.82 +1.40% +6.71%

Sector ETFs
Symbol Price
Change
52-Wk
Oil Service 136.18 +1.51% +14.84%
Big Pharma 64.13 +0.61% -3.32%
Internet 72.13 +0.70% +22.34%
Semis 16.03 +2.10% +28.86%
Utilities 31.21 +0.29% +1.56%
Defense 18.51 +1.26% +10.11%
Nanotech 9.99 +1.32% 0.00%
Alt. Energy 9.95 +1.43% -4.42%
Water 18.31 +1.10% +12.19%
Insurance 16.07 +1.20% +18.34%
Biotech 20.58 +1.08% +27.12%
Retail 19.65 +0.10% +28.43%
Software 24.59 +0.94% +24.07%
Big Tech 53.73 +1.02% +21.92%
Construction 12.99 +2.12% +13.25%
Media 13.57 +1.12% +24.95%
Consumer Svcs 67.26 +0.81% +23.30%
Financials 54.87 +2.39% +5.18%
Health Care 64.22 +0.74% +1.31%
Industrials 63.25 +1.61% +19.70%
Basic Mat 73.57 +1.56% +21.56%
Real Estate 55.24 +1.36% +23.77%
Transportation 91.17 +1.35% +25.60%
Telecom 22.48 +1.08% +17.08%