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This Fall Will Be Crazy for These Biotech Stocks

By Dr. George Huang
Friday, October 16, 2009

Most speculators have it all wrong when it comes to biotech trading...
 
They'll buy biotech stocks ahead of FDA decisions, hoping an approval will bring 100% overnight gains. But more often than not, the market is one step ahead. The stock price will creep up as everyone anticipates good news.
 
At best, you'll see 10% to 20% gains in most cases. Not bad. But the risk is outrageous: An unexpected rejection will slice 50% to 90% off your shares.
 
There's a better way to trade these roller-coaster events. A 10-year back study showed this strategy returns 50% annually. Here's what you do...
 
In short, simply wait for setbacks and buy great companies on the cheap.
 
This strategy has proved wildly successful over the past 18 months. For example, last June, a biotech called Indevus ran into a regulatory roadblock, and the stock lost 70% of its value. If you held shares, that probably hurt.
 
But once shares had fallen that far, I figured they were 50% undervalued, even taking the worst-case scenario into account. It was a can't-lose trade. Sure enough, my S&A FDA Report readers cashed out for a 60% gain six months later.
 
We did the same with Theravance and Viropharma. We pocketed gains of 58% and 44%, respectively, in less than a year as these stocks recovered from brutal FDA rejections.
 
A few months back, I gave you a handful of stocks to watch for FDA rejections. I was hoping we could pick up a couple on the cheap for similar returns. Miraculously, the FDA approved every single drug on the list. Not a problem. For the strategy to work properly, patience is a must.
 
And thankfully, there's always a new drug up for FDA approval. Here are the highlights for the next few weeks:
 
Date
Company
Drug
Target
Oct 19
Amgen (AMGN)
Prolia
Osteoporosis
Oct 22
Acorda (ACOR)
Fampridine SR
Multiple Sclerosis
Oct 30
GTX
(GTXI)
Acapodene
Prostate Cancer
Nov 9
Xenoport (XNPT)
XP13512
Restless Leg Syndrome
Nov 13
Cadence (CADX)
Acetavance
Pain
 
Amgen's new osteoporosis drug, Prolia, is up for approval later this month. The biotech behemoth is hoping the twice-yearly injection can reinvigorate its stalling sales (and stock price).
 
Given a clean bill of health from the FDA, Prolia will become a multibillion-dollar seller and Amgen shares could top $70 by yearend – a 15% gain from here. But if Prolia hits a snag, investors will dump Amgen in droves. In that case, we may get to own the largest biotech in the world at a once-in-a-decade price. I'd look to buy below $50.
 
The remaining decisions on the list will be even bigger stock-moving events. For example, if Acorda, GTX, Xenoport, and Cadence can win approval for their drugs, these tiny biotechs could eventually become profitable. But rejections for any will mean a short-term disaster for shareholders.
 
I consider all four companies worthy FDA Report candidates at the right price. Each has good management, multiple drugs in the pipeline, and will eventually recover. Circle the decision dates on your calendar... and be on the lookout for deals.
 
Good investing,
 
George Huang




Market Notes
Big Pharma breaks out... Novartis, Sanofi-Aventis, GlaxoSmithKline, Merck, Schering-Plough, and Bristol-Myers make new highs.
 
Crude jumps to new high over $77 per barrel.
 
10-year yield surges... Treasury rate sees two-week climb from 3.1% to 3.43%.
 
Earnings today... Bank of America, General Electric, Halliburton, Mattel.
Market Watch
Symbol Price
Change
52-Wk
S&P 500 1221.53 +1.28% +10.12%
Oil 37.77 +1.53% -2.75%
Gold 135.20 -0.13% +13.44%
Silver 27.93 +0.43% +47.86%
US-Dollar 80.67 -0.81% +8.09%
Euro 1.32 +0.64% -12.10%
Volatility 19.39 -9.22% -8.19%
Gold Stocks 564.53 +1.34% +10.57%
10-Year Yield 3.00 +1.35% -9.64%

World ETFs
Symbol Price
Change
52-Wk
USA 122.56 +1.28% +10.17%
Canada 30.44 +1.33% +13.84%
Russia 21.63 +2.27% +16.67%
India 37.73 +1.92% +19.97%
Israel 16.47 +0.86% +9.65%
Japan 10.58 +0.95% +7.41%
Singapore 13.88 +1.02% +19.24%
Taiwan 14.72 +1.59% +17.76%
S. Korea 56.56 +1.67% +22.80%
S. Africa 70.85 +3.89% +22.94%
China 45.06 +1.37% +0.13%
Lat.America 52.82 +1.40% +6.71%

Sector ETFs
Symbol Price
Change
52-Wk
Oil Service 136.18 +1.51% +14.84%
Big Pharma 64.13 +0.61% -3.32%
Internet 72.13 +0.70% +22.34%
Semis 16.03 +2.10% +28.86%
Utilities 31.21 +0.29% +1.56%
Defense 18.51 +1.26% +10.11%
Nanotech 9.99 +1.32% 0.00%
Alt. Energy 9.95 +1.43% -4.42%
Water 18.31 +1.10% +12.19%
Insurance 16.07 +1.20% +18.34%
Biotech 20.58 +1.08% +27.12%
Retail 19.65 +0.10% +28.43%
Software 24.59 +0.94% +24.07%
Big Tech 53.73 +1.02% +21.92%
Construction 12.99 +2.12% +13.25%
Media 13.57 +1.12% +24.95%
Consumer Svcs 67.26 +0.81% +23.30%
Financials 54.87 +2.39% +5.18%
Health Care 64.22 +0.74% +1.31%
Industrials 63.25 +1.61% +19.70%
Basic Mat 73.57 +1.56% +21.56%
Real Estate 55.24 +1.36% +23.77%
Transportation 91.17 +1.35% +25.60%
Telecom 22.48 +1.08% +17.08%

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